give up
US /ɡɪv ˈʌp/
UK /ɡɪv ˈʌp/

1.
rendirse, abandonar
to stop trying to do something; to abandon an effort or task
:
•
Don't give up on your dreams.
No te rindas con tus sueños.
•
After many attempts, he decided to give up.
Después de muchos intentos, decidió rendirse.
2.
dejar, ceder
to stop doing or having something, especially a habit or possession
:
•
You should give up smoking for your health.
Deberías dejar de fumar por tu salud.
•
He had to give up his seat to an elderly woman.
Tuvo que ceder su asiento a una mujer mayor.