in the teeth of

US /ɪn ðə tiːθ əv/
UK /ɪn ðə tiːθ əv/
"in the teeth of" picture
1.

a pesar de, frente a

in spite of; despite (something difficult or dangerous)

:
They continued their journey in the teeth of a raging blizzard.
Continuaron su viaje a pesar de una furiosa ventisca.
The company launched the new product in the teeth of strong competition.
La empresa lanzó el nuevo producto a pesar de la fuerte competencia.