vendetta
US /venˈdet̬.ə/
UK /venˈdet̬.ə/

1.
a blood feud in which the family of a murdered person seeks vengeance on the murderer or the murderer's family
:
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The two families were locked in a bitter vendetta for generations.
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The novel explores the theme of a family vendetta.
2.
a prolonged bitter quarrel with or campaign against someone
:
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The politician claimed the accusations were part of a personal vendetta against him.
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The newspaper launched a vendetta against the corrupt official.