tie someone (up) in knots
US /taɪ ˈsʌm.wʌn ʌp ɪn nɑːts/
UK /taɪ ˈsʌm.wʌn ʌp ɪn nɑːts/

1.
iemand in de war brengen, iemand nerveus maken
to confuse someone or make them feel very worried or anxious
:
•
The complicated instructions really tied me up in knots.
De ingewikkelde instructies brachten me echt in de war.
•
The thought of the exam is tying her up in knots.
De gedachte aan het examen maakt haar erg nerveus.