once in a lifetime

US /wʌns ɪn ə ˈlaɪfˌtaɪm/
UK /wʌns ɪn ə ˈlaɪfˌtaɪm/
"once in a lifetime" picture
1.

一生に一度の, 千載一遇の

an event or opportunity that is very rare and unlikely to happen again in a person's life

:
Seeing the total solar eclipse was a once in a lifetime experience.
皆既日食を見るのは一生に一度の経験だった。
This opportunity to travel the world is truly a once in a lifetime chance.
世界を旅するこの機会は、まさに一生に一度のチャンスだ。