profound
US /prəˈfaʊnd/
UK /prəˈfaʊnd/

1.
2.
profundo, perspicaz
(of a state, quality, or emotion) very great or intense
:
•
His death had a profound effect on her.
Su muerte tuvo un efecto profundo en ella.
•
The book offers profound insights into human nature.
El libro ofrece ideas profundas sobre la naturaleza humana.