lose the plot
US /luːz ðə plɑt/
UK /luːz ðə plɑt/

1.
perder los papeles, perder el rumbo, volverse loco
to become unable to understand what is happening or to control your emotions
:
•
After working for 18 hours straight, I started to lose the plot.
Después de trabajar 18 horas seguidas, empecé a perder los papeles.
•
The director seems to have lost the plot with this new movie.
El director parece haber perdido el rumbo con esta nueva película.