queen bee
US /ˈkwiːn biː/
UK /ˈkwiːn biː/

1.
the single fertile female in a colony of honeybees, responsible for laying all the eggs
:
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The beekeeper carefully located the queen bee in the hive.
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A healthy queen bee is essential for a thriving colony.
2.
a dominant or controlling woman, especially in a social group
:
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She's the undisputed queen bee of the office, everyone follows her lead.
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In high school, she was the queen bee of her clique.