drug
US /drʌɡ/
UK /drʌɡ/

1.
a medicine or other substance which has a physiological effect when ingested or otherwise introduced into the body.
:
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The doctor prescribed a new drug for her condition.
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Many common drugs can be bought over the counter.
2.
an illegal substance that causes addiction, habituation, or a marked change in consciousness, mood, or behavior.
:
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He was arrested for possession of illegal drugs.
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The government is trying to combat the spread of illicit drugs.
1.
add a narcotic or other drug to (food or drink).
:
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Someone must have drugged his drink.
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The kidnappers drugged their victim to keep her quiet.