lose your shirt
US /luːz jʊər ʃɜːrt/
UK /luːz jʊər ʃɜːrt/

1.
输光所有钱, 损失惨重
to lose a lot of money, especially by gambling or a bad investment
:
•
He lost his shirt at the casino last night.
他昨晚在赌场输光了所有钱。
•
Many investors lost their shirts during the stock market crash.
许多投资者在股市崩盘期间损失惨重。