let somebody/something loose
US /lɛt ˈsʌmˌbɑːdi ˈsʌmˌθɪŋ luːs/
UK /lɛt ˈsʌmˌbɑːdi ˈsʌmˌθɪŋ luːs/
1.
放开, 放任
to allow a person or animal to be free, or to allow something to be used or to happen without control
:
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The zookeepers decided to let the animals loose in the larger enclosure.
动物园管理员决定放开动物们到更大的围栏里。
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Once he gets a microphone, he just lets himself loose and talks for hours.
一旦拿到麦克风，他就会放开自己，滔滔不绝地讲上几个小时。