have a screw loose
US /hæv ə skruː luːs/
UK /hæv ə skruː luːs/

1.
有点不正常, 脑子有毛病
to be slightly mad or eccentric
:
•
I think he might have a screw loose; he talks to himself all the time.
我觉得他可能有点不正常;他总是自言自语。
•
Only someone who has a screw loose would try to climb that mountain in winter.
只有脑子有问题的人才会在冬天尝试爬那座山。