go against the grain
US /ɡoʊ əˈɡɛnst ðə ɡreɪn/
UK /ɡoʊ əˈɡɛnst ðə ɡreɪn/
1.
违背本性, 与众不同, 逆潮流而动
to be contrary to one's natural inclination or to generally accepted norms or practices
:
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It really goes against the grain for him to ask for help, as he's always been so independent.
对他来说，寻求帮助真的违背了他的本性，因为他一直都很独立。
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Her decision to pursue art went against the grain of her family's expectations for her to become a doctor.
她追求艺术的决定违背了家人希望她成为医生的期望。