give something your best shot
US /ɡɪv ˈsʌmθɪŋ jʊər bɛst ʃɑt/
UK /ɡɪv ˈsʌmθɪŋ jʊər bɛst ʃɑt/

1.
尽力而为, 全力以赴
to try as hard as you can to do something, even if you are not sure you will succeed
:
•
I don't know if I'll win, but I'm going to give it my best shot.
我不知道我是否会赢,但我会尽力而为。
•
Even if it's a tough challenge, you should always give it your best shot.
即使这是一个艰难的挑战,你也应该始终尽力而为。