tie someone (up) in knots
US /taɪ ˈsʌm.wʌn ʌp ɪn nɑːts/
UK /taɪ ˈsʌm.wʌn ʌp ɪn nɑːts/

1.
使某人困惑, 使某人非常焦慮
to confuse someone or make them feel very worried or anxious
:
•
The complicated instructions really tied me up in knots.
那些複雜的說明真的把我搞糊塗了。
•
The thought of the exam is tying her up in knots.
一想到考試就讓她非常焦慮。