profound
US /prəˈfaʊnd/
UK /prəˈfaʊnd/

1.
2.
profundo, perspicaz
(of a state, quality, or emotion) very great or intense
:
•
His death had a profound effect on her.
A morte dele teve um efeito profundo nela.
•
The book offers profound insights into human nature.
O livro oferece insights profundos sobre a natureza humana.