in spite of

US /ɪn spaɪt ʌv/
UK /ɪn spaɪt ʌv/
"in spite of" picture
1.

にもかかわらず, をものともせずに

without being affected by the particular fact mentioned

:
In spite of the rain, we went for a walk.
にもかかわらず、私たちは散歩に出かけた。
She succeeded in spite of many difficulties.
彼女は多くの困難にもかかわらず成功した。