alienation
US /ˌeɪ.li.əˈneɪ.ʃən/
UK /ˌeɪ.li.əˈneɪ.ʃən/
1.
疎外
the feeling that you have no connection with the people around you or that you are not part of a group:
:
•
Depressed people frequently feel a sense of alienation from those around them.