adverse

US /ædˈvɝːs/
UK /ædˈvɝːs/
"adverse" picture
1.

不利な, 有害な, 逆の

preventing success or development; harmful; unfavorable

:
The company faced adverse economic conditions.
その会社は不利な経済状況に直面した。
Smoking has many adverse effects on health.
喫煙は健康に多くの悪影響を及ぼす。