give up
US /ɡɪv ˈʌp/
UK /ɡɪv ˈʌp/

1.
arrendersi, rinunciare
to stop trying to do something; to abandon an effort or task
:
•
Don't give up on your dreams.
Non arrenderti ai tuoi sogni.
•
After many attempts, he decided to give up.
Dopo molti tentativi, decise di arrendersi.
2.
smettere, cedere
to stop doing or having something, especially a habit or possession
:
•
You should give up smoking for your health.
Dovresti smettere di fumare per la tua salute.
•
He had to give up his seat to an elderly woman.
Ha dovuto cedere il suo posto a una donna anziana.