substantive

US /səbˈstæn.t̬ɪv/
UK /səbˈstæn.t̬ɪv/
1.

substantiel

having a firm basis in reality and therefore important, meaningful, or considerable.

:
there is no substantive evidence for the efficacy of these drugs
2.

substantiel

having a separate and independent existence.

1.

substantiel

a noun.