despair

US /dɪˈsper/
UK /dɪˈsper/
1.

tuyệt vọng

the feeling that there is no hope and that you can do nothing to improve a difficult or worrying situation:

:
Hope began to fade, leaving a mood/sense of despair.
1.

tuyệt vọng

to feel despair about something or someone:

:
Don't despair! We'll find a way out!