the odds are stacked against you
US /ðə ɑːdz ɑː stækt əˈɡɛnst ju/
UK /ðə ɑːdz ɑː stækt əˈɡɛnst ju/

1.
the chances of you succeeding are very small
:
•
He knows the odds are stacked against him, but he's still going to try.
•
With so many experienced competitors, the odds are stacked against you.