the end of the line
US /ðɪ ˈɛnd əv ðə laɪn/
UK /ðɪ ˈɛnd əv ðə laɪn/

1.
the point at which a process, activity, or series of events must stop or come to an end
:
•
After years of struggling, he realized he had reached the end of the line with his business.
•
If we don't find a solution soon, this project will be the end of the line.