the end of the line

US /ðɪ ˈɛnd əv ðə laɪn/
UK /ðɪ ˈɛnd əv ðə laɪn/
"the end of the line" picture
1.

the point at which a process, activity, or series of events must stop or come to an end

:
After years of struggling, he realized he had reached the end of the line with his business.
If we don't find a solution soon, this project will be the end of the line.