systemic
US /sɪˈstem.ɪk/
UK /sɪˈstem.ɪk/
1.
relating to a system, especially as opposed to a particular part.
:
•
the disease is localized rather than systemic
2.
denoting the part of the circulatory system concerned with the transportation of oxygen to and carbon dioxide from the body in general, especially as distinct from the pulmonary part concerned with the transportation of oxygen from and carbon dioxide to the lungs.