runner's high
US /ˈrʌnərz haɪ/
UK /ˈrʌnərz haɪ/

1.
a feeling of euphoria and reduced pain experienced during or after sustained exercise, especially running, attributed to the release of endorphins.
:
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After ten miles, she finally hit the runner's high and felt like she could run forever.
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Many long-distance athletes train specifically to achieve a runner's high.