operate
US /ˈɑː.pə.reɪt/
UK /ˈɑː.pə.reɪt/

1.
2.
perform a surgical operation
:
•
The surgeon will operate on her knee tomorrow.
•
He had to operate immediately to save the patient's life.
3.
be in action or have an effect
:
•
The new policy will operate from next month.
•
These principles operate in all aspects of life.