mutation
US /mjuːˈteɪ.ʃən/
UK /mjuːˈteɪ.ʃən/

1.
the action or process of changing in form or nature
:
•
The virus underwent a rapid mutation.
•
The company is undergoing a significant mutation in its business model.
2.
a change or alteration in form or nature
:
•
Genetic mutations can lead to new traits.
•
Some diseases are caused by a single gene mutation.