lose your shirt
US /luːz jʊər ʃɜːrt/
UK /luːz jʊər ʃɜːrt/

1.
to lose a lot of money, especially by gambling or a bad investment
:
•
He lost his shirt at the casino last night.
•
Many investors lost their shirts during the stock market crash.
to lose a lot of money, especially by gambling or a bad investment