Down syndrome
US /ˈdaʊn ˌsɪn.droʊm/
UK /ˈdaʊn ˌsɪn.droʊm/

1.
a congenital disorder arising from a chromosome defect, causing intellectual impairment and physical abnormalities including short stature and a broad facial profile. It arises from the presence of an extra chromosome 21.
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Children with Down syndrome often benefit from early intervention programs.
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Awareness campaigns help to promote understanding and acceptance of individuals with Down syndrome.