derail

US /ˌdiːˈreɪl/
UK /ˌdiːˈreɪl/
"derail" picture
1.

cause (a train or tram) to leave its tracks accidentally

:
•
The heavy snow caused the train to derail.
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An investigation is underway to determine why the train derailed.
:
run off the railsleave the tracks
2.

prevent (a plan or process) from continuing as intended

:
•
His sudden resignation threatened to derail the entire project.
•
Don't let minor setbacks derail your progress.
:
disruptthwartfrustratesabotageimpede