chronic fatigue syndrome
US /ˌkrɑː.nɪk fəˈtiːɡ ˈsɪn.droʊm/
UK /ˌkrɑː.nɪk fəˈtiːɡ ˈsɪn.droʊm/

1.
a medical condition characterized by long-term fatigue and other symptoms that limit a person's ability to perform ordinary daily activities
:
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She was diagnosed with chronic fatigue syndrome after years of unexplained exhaustion.
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Living with chronic fatigue syndrome can be very challenging.