antagonize

US /ænˈtæɡ.ə.naɪz/
UK /ænˈtæɡ.ə.naɪz/
"antagonize" picture
1.

to make someone hostile or unfriendly; to provoke or annoy someone

:
Try not to antagonize your little brother; he's already upset.
His rude comments only served to antagonize the audience.